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Targeted Cancer Therapies

Use of drugs to more precisely identify and attack cancer cells, based on a person’s genes

What are Targeted Cancer Therapies?

Targeted cancer therapies use drugs to more precisely identify and attack cancer cells, based on a person’s genes, as compared to traditional cancer treatments. As such, targeted cancer therapies are sometimes called “molecularly targeted drugs” or “molecularly targeted therapies” and allow for a more precision medicine approach.

In addition to being molecularly-focused, targeted therapies are often cytostatic (which means they block tumor cell proliferation), whereas standard chemotherapy agents are cytotoxic (which means they kill tumor cells). Therefore, many targeted drugs go after the mechanisms that make cancer cells different than normal cells and leave the healthy cells alone.

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Researchers Working On Targeted Cancer Therapies

James P. Basilion, Ph.D.
Case Western Reserve University
Ronald A. DePinho, M.D.
University of Texas MD Anderson Cancer Center
Ronald A. DePinho, M.D. University of Texas MD Anderson Cancer Center
Rakesh K. Jain, Ph.D.
Massachusetts General Hospital & Harvard Medical School
Cesare Spadoni, Ph.D.
University of London
Laurence Hurley, Ph.D.
University of Arizona
Alanna Schepartz, Ph.D.
Yale University
William L. Jorgensen, Ph.D.
Yale University

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