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February 25, 2026

[vc_row][vc_column][vc_single_image image="67187" img_size="full" alignment="center" css=""][/vc_column][/vc_row][vc_row][vc_column][vc_column_text css=""]Researchers have found a promising biomarker that may help doctors predict which patients with extensive-stage small cell lung cancer (ES-SCLC) are most likely to respond to tarlatamab. This targeted immunotherapy is possible because of new insights into DLL3 biology, partially...

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May 28, 2025

[vc_row][vc_column][vc_single_image image="64144" img_size="full" alignment="center" css=""][/vc_column][/vc_row][vc_row][vc_column][vc_column_text css=""]A new article by NFCR-supported scientist Dr. Valerie Weaver, titled "Tissue Mechanics in Tumor Heterogeneity and Aggression" (PMID: 40307158), was published in the April 2025 issue of Trends in Cancer. The article provides a comprehensive review of how the tumor...

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March 12, 2025

[vc_row][vc_column][vc_single_image image="63312" img_size="full" alignment="center" css=""][vc_column_text css=""]NFCR-supported researcher Dr. Xiang-Lei Yang of Scripps Research has published a new paper titled "Seryl-tRNA synthetase inhibits Wnt signaling and breast cancer progression and metastasis." This study discusses the role of seryl-tRNA synthetase (SerRS) in regulating Wnt signaling, a pathway known to be...

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February 11, 2025

[vc_row][vc_column][vc_single_image image="63123" img_size="full" alignment="center" css=""][vc_column_text css=""]NFCR-supported researchers Dr. Suzanne Topalian of Johns Hopkins University and her collaborator Dr. Paul Nghiem of the University of Washington co-authored a study titled "A minimal gene set characterizes TIL specific for diverse tumor antigens across different cancer types" that...

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January 14, 2025

[vc_row][vc_column][vc_single_image image="62971" img_size="full" alignment="center" css=""][vc_column_text css=""]Two NFCR-supported researchers have recently published in the high-impact publication Nature Communications for their work on liquid biopsies and circulating tumor cells. Drs. Daniel A. Haber of Massachusetts General Hospital Cancer Center and Aditya Bardia of the University of California,...

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September 13, 2022

[vc_row][vc_column][vc_video link="https://www.youtube.com/watch?v=5xkfbQKugxY&t"][vc_column_text]Pancreatic cancer is one of the most lethal malignancies with few treatment options. Its five-year survival rate is only about 10% in the US. Several treatment options are available for pancreatic cancers, including surgery, chemotherapy, radiation therapy, immunotherapy, and combinational therapies. However, these therapies...

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August 25, 2021

[vc_row][vc_column][vc_single_image image="44195" img_size="full"][vc_empty_space height="22px"][/vc_column][/vc_row][vc_row][vc_column][vc_column_text css=""]Learning that cancer has spread, or metastasized, used to be the moment people lost hope. To know that cancer had grown and infected other healthy parts of the body sent shivers down the spines of both doctors and patients alike. Thankfully, dedicated...

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December 15, 2020

[vc_row][vc_column][vc_column_text css=""] New approach developed by Dr. Rakesh Jain and his research team identifies biomarkers that may indicate which patients will best respond to immune checkpoint blockade therapies. A research team led by NFCR-supported scientist Rakesh K. Jain, PhD, the Andrew Werk Cook Professor of Tumor Biology...

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March 25, 2019

[vc_row][vc_column][vc_single_image image="25383" img_size="full" alignment="center"][/vc_column][/vc_row][vc_row][vc_column][vc_column_text css=""] “It’s what I consider the most interesting science in the world,” says NFCR Fellow Danny Welch, Ph.D. He is alluding to his work discovering the presence of metastasis-suppressing genes in human DNA. Welch, the Hall Family Professor of Molecular Medicine, a professor...

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